ST 271

Research use only, not for human use.

ST271 is an effective protein tyrosine kinase (PTK) inhibitor.

ST-271 is tyrphostin tyrosine kinase inhibitor. ST271 reduced intracellular Ca2+ levels and inhibited activation of phospholipase C. Elevation of intracellular Ca2+ regulates agonist-induced activation of phospholipase C and that this contributes to the inhibition of thrombin-induced formation of inositol phosphates by the tyrphostin ST271.

ST271 partially inhibits peptide phosphorylation in the membrane preparation and in permeabilized platelets. ST271 (100 μM) causes complete inhibition of formation of inositol phosphates induced by FcγRII cross-linking, but also induces a small (< 30%) but significant inhibition of the response to thrombin and U46619.

——

ST-271 | ST271 | ST 271

Others

Other Targets

PTK

——

——

106392-48-7

272.34

C16H20N2O2

>98% (HPLC)

DMSO : ≥ 110 mg/mL 403.91 mM

CC(C)c1cc(cc(c1O)C(C)C)/C=C(\C#N)/C(=O)N

(E)-2-Cyano-3-[4-hydroxy-3,5-di(propan-2-yl)phenyl]prop-2-enamide

(-20℃)

With Ice Pack

≥ 2 years